对节日查现场药物测试的光谱技术的评估
N Meert1, J Eliaerts1, F Van Durme1
1Drugs and Toxicology, National Institute for Criminalistics and Criminology, Brussels, Belgium.
Drug testing and analysis
|August 5, 2024
概括
节日的现场毒品测试对于执法部门至关重要. 富里埃变换红外光谱法 (FT-IR) 显示出比拉曼光谱法更高的灵敏度,用于识别各种受控物质,特别是液体和片剂形式.
科学领域:
- 法医科学 法医科学 法医科学
- 分析化学 分析化学
- 频谱学是一种光谱学.
背景情况:
- 在节日上使用非法毒品需要快速的现场识别方法来执行法律.
- 传统的实验室分析耗时,阻碍了立即干预.
- 光谱技术为快速,非破坏性的药物查提供了潜力.
研究的目的:
- 为了比较拉曼光谱和富里埃变换红外光谱 (FT-IR) 的性能,用于现场药物查获分析.
- 评估这些技术对各种药物形式的有效性,包括药片,粉末,水晶和液体.
- 评估使用FT-IR与化学测量的可行性,以估计药物剂量.
主要方法:
- 使用拉曼光谱 (通过包装) 和FT-IR光谱 (同质化样本) 对166种药物样本进行现场分析.
- 将化学模型应用于FT-IR光谱,以估计MDMA药片剂量.
- 在法医实验室使用气体染色学-质谱学 (GC-MS) 和气体染色学-火焰电离检测 (GC-FID) 验证结果.
主要成果:
- 在所有样本类型中,FT-IR实现了超过95%的总体灵敏度.
- 拉曼光谱显示粉末 (100%) 和晶体 (81%) 的高灵敏度,但液体 (67%) 和片 (41%) 的灵敏度较低.
- 最常被扣押的药物是MDMA,可卡因和胺;MDMA剂量在药片中从52毫克到336毫克不等.
结论:
- 建议将拉曼光谱和FT-IR光谱结合起来,以便快速地在现场识别各种毒品获.
- FT-IR光谱对于分析液体和平板电脑特别有效,提供高灵敏度.
- 优化设置,内部光谱库和训练有素的操作人员对于准确的现场光谱分析至关重要.
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