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Updated: Jun 12, 2026

Measuring Single-Cell Mitochondrial DNA Copy Number and Heteroplasmy Using Digital Droplet Polymerase Chain Reaction
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在单细胞水平上实时评估线粒体DNA异质体动态

Rodaria Roussou1,2, Dirk Metzler1, Francesco Padovani3

  • 1Faculty of Biology, Ludwig-Maximilians-Universität München, 82152, Planegg-Martinsried, Germany.

The EMBO journal
|August 5, 2024
PubMed
概括

在活酵母中追踪线粒体DNA (mtDNA) 变体,发现细胞分裂期间的非对称分区和有限的线粒体融合/裂变. 这些因素驱动mtDNA异质体动力学和变异分离.

关键词:
异质塑性是一种异质塑性.数学建模的数学建模线粒体中的线粒体.线粒体分裂 线粒体分裂我们的mtDNA mtDNA

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