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Brain Imaging

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...

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Updated: Jun 17, 2025

Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms

Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms

Published on: March 21, 2019

在休息状态功能性脑成像中超越处理和分析相关的变化.

Xinhui Li¹, Nathalia Bianchini Esper¹, Lei Ai¹

¹Child Mind Institute, New York, NY, USA.

Nature human behaviour

|August 5, 2024

概括

功能性磁共振成像预处理管道的差异限制了可重现性. 即使有相同的数据,这些管道的变化也会降低大脑范围关联研究结果的一致性.

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Cerebral Blood Flow-Based Resting State Functional Connectivity of the Human Brain using Optical Diffuse Correlation Spectroscopy

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Profiling Maternal Behavior Responses During Whole-Brain Imaging

Profiling Maternal Behavior Responses During Whole-Brain Imaging

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Last Updated: Jun 17, 2025

Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms

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科学领域:

神经成像是一种神经成像.
神经科学是一个神经科学.
医疗成像医学成像

背景情况:

由于缺乏标准化的方法,科学中的可复制性受到挑战.
功能性神经成像缺乏关于地面真相和处理管道的共识.
这种变异性阻碍了跨研究的比较和可靠的科学结论.

研究的目的:

批判性地评估不同功能磁共振成像 (fMRI) 预处理管道中变化的影响.
评估管道差异如何影响评价者之间的可靠性和研究结果的一致性.
在fMRI研究中识别限制可重现性的因素.

主要方法:

5个独立开发的fMRI数据最小预处理管道的比较.
分析通过每个不同的管道处理的相同数据集.
评估管道间协议及其对后续分析的影响.

主要成果:

即使在处理相同的fMRI数据时,也观察到适度的管道间协议.
低的管道间协议可以掩盖潜在的数据可靠性问题.
受损的管道间协议显著影响了全脑协会研究 (BWAS) 结果的一致性.

结论:

fMRI预处理管道的变化是限制交叉研究可重现性的关键因素.
分析配置的选择,包括常见和被忽视的决策,可以导致fMRI结果的实质差异.
分析管道的标准化评估对于提高神经成像研究的可靠性和一致性至关重要.