胎儿主要异常和相关的孕产妇,产科和新生儿结局
Inshirah Sgayer1,2, Tal Skliar3, Lior Lowenstein4,3
1Department of Obstetrics and Gynecology, Galilee Medical Center, 2210001, Nahariya, Israel. inshirah.sg.sh@gmail.com.
Archives of gynecology and obstetrics
|August 5, 2024
概括
怀孕期间主要的胎儿异常显著增加了母亲和新生儿的风险,导致更早的分娩,更多的并发症,如胎盘断裂,以及较高的死产和新生儿死亡率.
科学领域:
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 新生儿结局的结果.
- 怀孕并发症 怀孕并发症
背景情况:
- 主要的胎儿异常在单子妊娠中存在重大挑战.
- 了解相关的孕产妇和新生儿风险对于临床管理至关重要.
研究的目的:
- 调查由重大胎儿异常复杂的怀孕中的孕产妇,产科和新生儿后果.
- 为了将这些结果与对照组的怀孕与非异常胎儿进行比较.
主要方法:
- 一个10年的回顾性队列研究在一所高等大学医院进行.
- 在具有重大胎儿异常的怀孕和对照组之间比较了孕妇和产科结局.
主要成果:
- 有重大胎儿异常的孕妇在分娩时妊娠年龄显着较低 (37.0 vs 39.4周),早产率更高 (<37周和<32周).
- 观察到胎盘断裂率增加 (6.8%与0.9%相比),剖腹产 (53.8%与28.3%相比),产后出血 (11.3%与2.8%相比) 和高血压疾病 (9.5%与2.1%相比).
- 在异常组中,死胎 (17.1%对比0.3%) 和新生儿死亡 (12.5%对比0.0%) 的比率显著更高. 主要的胎儿异常与母亲的不良结果有关 (OR=2.47).
- 多水症是对母亲不良结果的独立风险因素 (OR=4.7).
结论:
- 由于重大胎儿异常而复杂的怀孕与母亲和新生儿不良后果的风险显著增加有关.
- 这些怀孕应该被管理为高风险,需要密切监测和专业护理.
- 在这种情况下,多水症被确定为对母亲不良结果的独立风险因素.
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