温度对经过全弓置换后过渡性神经功能障碍的影响
Keitaro Nakanishi1, Hiroshi Sato2, Yutaka Iba1
1Department of Cardiovascular Surgery, Sapporo Medical University School of Medicine, S1W16 Chuo-ku, Sapporo, Hokkaido, 060-8543, Japan.
General thoracic and cardiovascular surgery
|August 5, 2024
概括
在大动脉手术期间的过度冷却和快速冷却增加了在完全门置换后过渡性神经功能障碍的风险. 这些发现强调了控制冷却策略对于预防脑损伤的重要性.
科学领域:
- 心血管外科心血管外科
- 神经学 神经学
- 低温研究研究 低温研究
背景情况:
- 术内冷却对大动脉手术后神经学结果的影响尚不清楚.
- 过渡性神经功能障碍 (TND) 是大动脉门置换后的潜在并发症.
研究的目的:
- 调查手术内冷却状态与全弓置换后TND发生率之间的关联.
- 为了确定可能预测TND的特定冷却参数.
主要方法:
- 分析了228名患者的耳温度趋势,这些患者接受了全门置换和低温循环停止.
- 评估冷却参数,包括最低温度,冷却速度和冷却区域 (冷却程度).
- 统计分析以确定冷却变量与TND之间的关系.
主要成果:
- 在14.5%的患者中发生了TND.
- 与没有TND的患者相比,TND的患者表现出更大的冷却面积和更高的冷却速度.
- 多变量分析确定了冷却面积和冷却速度作为TND的独立风险因素.
结论:
- 冷却程度 (冷却区域) 和冷却速度都与TND.显著相关.
- 过度冷却和过快的冷却可能会导致术后脑损伤.
- 在大动脉手术期间优化冷却策略对于减轻神经系统并发症至关重要.
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