在西班牙,十二种可通过免疫预防的传染病对人口健康的影响,使用因残疾调整的寿命年 (DALYs)
Alberto Pérez-Rubio1, Jorge Mestre-Ferrandiz2, Juan Luis López-Belmonte3
1Medical Direction, Complejo Asistencial de Ávila, Ávila, Spain.
BMC infectious diseases
|August 5, 2024
概括
免疫可预防的呼吸道感染在西班牙造成了严重的健康负担,特别是流感和呼吸道同胞病毒 (RSV). 这些发现指导了疾病预防和资源分配的公共卫生战略.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 传染性疾病 传染性疾病
背景情况:
- 估计传染病负担对于公共卫生规划至关重要.
- 欧洲传染病负担 (BCoDE) 方法为此类估计提供了一个框架.
- 西班牙的国家免疫计划需要持续评估其有效性和潜在的扩张.
研究的目的:
- 通过使用BCoDE方法来估计西班牙部分可通过免疫预防的传染病的疾病负担.
- 分析不同疾病对整体负担的贡献.
- 为国家免疫战略提供信息,并确定潜在的新疫苗目标.
主要方法:
- 基于发病率和病原体的方法BCoDE方法用于计算残疾调整寿命年 (DALY) 估计.
- 对于疹病毒,轮状病毒,呼吸道同胞病毒 (RSV) 和水,开发了新的结局树.
- 使用了西班牙特定的发病率,住院和死亡率数据,经过专家共识的验证.
主要成果:
- 总疾病负担为163.54年DALY/100,000人口,呼吸道感染约占90%.
- 流感 (110.00 DALYs/100,000),侵入性肺炎球菌病 (25.20 DALYs/100,000) 和RSV (10.57 DALYs/100,000) 是主要的原因.
- 老年人 (≥60岁) 和幼儿 (<5岁) 承受了更大的负担,RSV是婴儿 (<1岁) 的主要原因.
结论:
- 在西班牙,免疫可以预防的呼吸道感染的负担仍然很大.
- 这项研究强调了RSV造成的显著DALY负担,强调了其对公共卫生的影响.
- 这些发现提供了优先考虑干预措施和分配医疗保健资源以减轻西班牙疾病负担的证据.
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