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Updated: Jun 19, 2026

Depletion and Reconstitution of Macrophages in Mice
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在小鼠的MRONJ发育过程中巨细胞极化

A Soundia1, N Elzakra2, D Hadaya2

  • 1Private practice, Kennewick, WA, USA.

Journal of dental research
|August 6, 2024
PubMed
概括

与药物相关的下巴骨髓缩 (MRONJ) 涉及M1巨细胞两极分化. 罗西格利塔逆转了这种M1偏好,并减少了小鼠的MRONJ负担,这表明M2促进是治疗策略.

关键词:
骨生物学 骨生物学 骨生物学免疫力是一种免疫力.这是一种炎症炎症炎症炎症.骨质结核病的结核病.牙周病 (牙周病) /牙周炎 (牙周炎)牙周组织/牙周组织.

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Mouse Models of Cancer Study02:43

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Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...