从2010年到2021年,澳大利亚的多发性硬化症患病率显著增加
Julie A Campbell1, Steve Simpson-Yap2,3,4,5, Bruce V Taylor1
1MS Research Flagship, Menzies Institute for Medical Research, University of Tasmania, Hobart, TAS, Australia.
Multiple sclerosis (Houndmills, Basingstoke, England)
|August 6, 2024
概括
多发性硬化症 (MS) 患病率在澳大利亚继续上升,在2017年至2021年期间观察到显著增加. 这一趋势反映了全球模式,强调了需要有效的MS预防策略.
科学领域:
- 神经学 神经学
- 流行病学 流行病学
背景情况:
- 全球多发性硬化症 (MS) 患病率正在增加.
- 澳大利亚的MS流行趋势需要更新调查.
研究的目的:
- 为了确定多发性硬化症 (MS) 患病率是否在澳大利亚继续增加.
- 使用经过验证的基于处方的确定方法进行准确的估计.
主要方法:
- 从制药福利计划 (2021) 中提取疾病修饰疗法 (DMT) 处方.
- 使用澳大利亚MS纵向研究计算DMT透率.
- 根据DMT透率和人口估计进行调整;根据国家/地区的年龄标准化流行率.
- 将2021年的估计数据与2010年和2017年的数据进行比较,使用波桑回归.
主要成果:
- 澳大利亚在2021年记录了33335名多发性硬化症患者,比2017年增加了30.2%.
- 年龄标准化患病率上升至每10万人口中的136.1.
- 一个积极的度梯度持续存在,塔斯马尼亚显示了最高的患病率.
结论:
- 多发性硬化症 (MS) 患病率在澳大利亚不断上升,与全球趋势一致.
- 在更高度地区发现更高的患病率.
- 迫切关注MS预防是减轻这一趋势的关键.
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