在老鼠的呼吸和吞过程中,状腺肌肉的功能参与
Nobuaki Saka1, Titi Chotirungsan1,2, Midori Yoshihara1
1Division of Dysphagia Rehabilitation, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
概括
状腺肌肉有助于呼吸和吞. 它在吞过程中的活动似乎是一种反射,不是中央控制的,受到气道狭窄和肌肉长度的影响.
科学领域:
- 身体生理学 身体生理学
- 呼吸机械学 呼吸机械
- 吞生理学的吞生理学
背景情况:
- 在呼吸和吞过程中,状腺肌肉在呼吸和吞过程中的作用尚未完全被理解.
- 研究其功能对于理解上呼吸道控制机制至关重要.
研究的目的:
- 为了确定状腺肌肉是否参与呼吸和吞反射.
- 分析呼吸道狭窄和固定肌肉长度如何调节肌肉活动.
主要方法:
- 在麻醉的老鼠中记录了,胃,甲状腺和腹膜肌肉的电肌图活动.
- 实验涉及正常呼吸,气道狭窄和固定的肌肉长度的条件.
主要成果:
- 状腺肌在吞时表现出吸气活动,并与其他上呼吸道肌肉协调.
- 气道狭窄增加了每个周期的所有肌肉的呼吸活动,但每秒仅在消化道,甲状腺和状腺活动.
- 呼吸道狭窄的吞活动便利性仅限于消化道肌肉.
- 在固定的长度时,状腺肌肉中没有吞活动,尽管保持了吸入活动.
结论:
- 在吸气过程中,状腺肌肉会轻微激活.
- 气道狭窄与隔膜相比,在上呼吸道肌肉中不同影响呼吸功能.
- 状腺肌肉的吞活动可能是一种肌肉反射,不是由吞的中央模式生成器直接控制的.
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