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Updated: Jun 17, 2025

SorLA and CLC:CLF-1-dependent Downregulation of CNTFRα as Demonstrated by Western Blotting, Inhibition of Lysosomal Enzymes, and Immunocytochemistry
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SorLA and CLC:CLF-1-dependent Downregulation of CNTFRα as Demonstrated by Western Blotting, Inhibition of Lysosomal Enzymes, and Immunocytochemistry

Published on: January 6, 2017

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RNF149通过无处化介导的CD63降解来负面调节LPS/TLR4信号传导

Xiu-An Yang1,2, Yingying Wang1, Mingyu Gong1

  • 1Laboratory of Genetic Engineering and Genomics, School of Basic Medical Sciences, Chengde Medical University, Chengde 067000, China.

Heliyon
|August 6, 2024
PubMed
概括

通过降解CD63.3,RNF149通过负面调节脂多糖类/托尔类受体4 (LPS/TLR4) 信号传递来降低CD63. 这项研究揭示了RNF149针对CD63的泛化和降解,影响TLR4通路活性.

关键词:
CD63 CD63 是一个在LPS/TLR4信号传输过程中,RNF1499 是一个字母.它们包括四西班牙素.乌比基因结合酶的使用.

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