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人类莱维体痴呆症动物模型中的认知功能障碍

Caroline Haikal1,2, Graham M Winston1,2, Michael G Kaplitt1,2

  • 1Weill Cornell Medicine, Department of Neurological Surgery, New York, NY, United States.

Frontiers in aging neuroscience
|August 6, 2024
PubMed
概括

这篇评论探讨了像帕金森病痴呆症这样的同核蛋白病变,重点关注认知障碍. 它检查了用于研究这些神经退行性疾病中的α-synuclein聚合和神经元死亡的各种动物模型.

关键词:
帕金森病是帕金森氏症的一种疾病.帕金森氏病痴呆症 痴呆症动物模型动物模型患有利维体痴呆症的痴呆症利维体痴呆症是什么意思预先形成的纤维素.

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Dementia01:30

Dementia

Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
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