跨直肠前列腺活检后感染的危险因素:基于人口的注册研究
Joakim Örtegren1,2, Kimia Kohestani1,3, Olof Elvstam4,5
1Department of Urology, Institute of Clinical Sciences, University of Gothenburg, Göteborg, Sweden.
European urology open science
|August 6, 2024
概括
跨直肠前列腺活检 (TPBx) 后的感染是一个风险,糖尿病和先前的尿路感染 (UTI) 是关键因素. 新发现显示下泌尿道症状,任何抗生素使用也会增加感染风险.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 跨直肠前列腺活检 (TPBx) 携带了手术后感染的风险.
- 识别可修改的风险因素对于提高TPBx安全性和潜在地避免替代活检途径至关重要.
研究的目的:
- 为了确定与TPBx后感染相关的临床风险因素.
- 在接受TPBx的患者中,为减轻感染风险的策略提供信息.
主要方法:
- 在瑞典 (2010-2019) 基于人口的TPBx程序的回顾性研究.
- 感染定义为30天内尿路感染或住院护理的抗生素处方.
- 包括糖尿病,先前的尿路感染,尿液培养和抗生素/BPH药物治疗史在内的因素的后勤回归分析.
主要成果:
- 7.0%的TPBx手术导致感染;2.9%导致住院治疗.
- 确定的危险因素:糖尿病,尿路感染的抗生素治疗,诺治疗和阳性尿液培养.
- 确定了较弱的危险因素:非尿路感染的抗生素治疗,BPH药物治疗和活检前的阴性尿液培养.
结论:
- 糖尿病和以前的尿路感染 (UTI) 是TPBx后感染的确诊危险因素.
- 下尿路症状和任何抗生素治疗都成为与感染相关的新风险因素.
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