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Updated: Jun 17, 2025

Solubility of Hydrophobic Compounds in Aqueous Solution Using Combinations of Self-assembling Peptide and Amino Acid
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使用人工智能技术在溶剂中药物溶解性的高级建模:对纳米化处理药物候选物的评估

Turki Al Hagbani1, Sameer Alshehri2, Sami Bawazeer3

  • 1Department of Pharmaceutics, College of Pharmacy, University of Hail, Hail, Saudi Arabia.

Frontiers in medicine
|August 6, 2024
PubMed
概括

断片多项式回归 (PPR) 最好预测二氧化碳在超临界的溶解度,优于内核回归 (KRR) 和Tweedie回归 (TDR). 与水循环算法 (WCA) 进行超参数调整,提高了这个关键制药过程的模型准确性.

关键词:
药物开发是药物的发展.机器学习是机器学习.建模建模是什么意思优化的优化优化优化.可溶性预测可溶性预测

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