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在甲状腺眼病中的眼外肌肉扩大使用体积分析

Kristen Park¹, Joy Li¹, Joyce Wen¹

¹Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, USA.

|August 6, 2024

概括

与普遍认为的相反,这项研究发现,上方直肠/上方眼复合体 (SRC) 在甲状腺眼病 (TED) 中通常最容易扩大,而不是下方直肠 (IR). 这一挑战在TED中确立了EOM扩大顺序.

科学领域:

眼科医生眼科眼科
内分泌学在内分泌学.
医疗成像医学成像

背景情况:

甲状腺眼病 (TED) 经常与眼外肌肉 (EOM) 的扩大有关.
传统的教学建议在TED中对EOM扩大进行特定的下降顺序:IR,MR,SR,LR,SO,IO.
最近的文献质疑了这种EOM参与的既定秩序.

研究的目的:

为了比较TED患者队列中的EOM体积.
在TED中调查EMO扩张的实际顺序.
挑战或证实通常被教导的肌肉参与序列.

主要方法:

追溯的,非随机的病例控制研究设计.
使用高分辨率CT扫描对28个TED轨道与31个正常轨道进行比较.
轨道软组织的手动细分和体积的统计比较.

主要成果:

与对照组相比,TED患者的上方直肠/上方眼综合体 (SRC) 和下方直肠 (IR) 体积显著增加.
平均SRC体积是2.3倍大,其次是IR (2.1倍),SO (1.8倍),MR (1.7倍),LR (1.6倍),IO (1.6倍) 和轨道脂肪 (1.4倍).
超过50%的TED轨道显示SRC或IR体积超过正常平均值的两个标准偏差.

结论:

这些发现表明,SRC可能是甲状腺眼病中受影响最严重的EOM.
这与之前接受的TED EOM扩展的下降顺序相矛盾.
该研究强调需要重新评估对EOM参与TED的典型理解.

关键词:

眼外肌肉眼外肌肉眼外肌肉眼外肌肉扩大眼外肌肉扩大下方直肠肌的肌肉是什么意思上方直肠综合体顶部直肠综合体甲状腺眼睛疾病甲状腺眼睛疾病

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