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Updated: Jun 17, 2025

Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors
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细胞内伊斯拉特拉维尔三酸盐半衰期支持延长剂量间隔

Xiaowei Zang1, Wendy Ankrom1, Walter K Kraft2

  • 1Merck & Co., Inc., Rahway, New Jersey, USA.

Antimicrobial agents and chemotherapy
|August 6, 2024
PubMed
概括

伊斯拉特拉维尔 (Islatravir) 是一种实验性口服抗逆转录病毒药物,其活性形式的长血半衰期为73小时,细胞内半衰期为195小时. 这些发现支持其作为长效艾滋病毒治疗的潜力.

关键词:
半衰期 半衰期 半衰期人类免疫缺陷病毒人类免疫缺陷病毒这是latravir的岛屿.核酸逆转录酶是一种核酸逆转录酶.药物动力学 药物动力学

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