电脑扫描输腔镜用于描述纤维增克罗恩病的可靠性
Florian Rieder1, Christopher Ma1, Jurij Hanzel1
1From the Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH 44195 (F.R.); Department of Gastroenterology, Hepatology, and Nutrition, Digestive Diseases and Surgery Institute and Program for Global Translational Inflammatory Bowel Diseases Research, Cleveland Clinic, Cleveland, Ohio (F.R., M.P., J.N., R.O.); Departments of Medicine and Community Health Sciences, Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada (C.M.); Alimentiv, London, Ontario, Canada (C.M., J.H., Z.W., L.G., L.M.S., J. Rémillard, G.Z., B.G.F., V.J.); Department of Gastroenterology, University of Ljubljana, University Medical Centre Ljubljana, Ljubljana, Slovenia (J.H.); Department of Radiology, Mayo Clinic, Rochester, Minn (J.G.F.); Section of Abdominal Imaging, Imaging Institute, Digestive Diseases and Surgery Institute and Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio (M.E.B.); Department of Radiology, University of California San Diego, San Diego, Calif (C.S.S.); Department of Radiology, IBD Unit, Hospital Clínic de Barcelona, Barcelona, Spain (N.C., J. Rimola); Pediatric and Adult Cardiothoracic and Vascular, Oncohematologic and Emergency Radiology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy (N.C.); Centre for Medical Imaging, University College London, London, England (S.A.T.); Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine and Science, Rochester, Minn (D.H.B.); and Departments of Medicine and Epidemiology and Biostatistics, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada (B.G.F., V.J.).
标准化的CT肠道测量可靠地描述克罗恩病的狭窄性. 狭窄的关键特征,如狭窄的长度,小肠的扩张和壁的厚度与严重程度相关,有助于临床决策.
科学领域:
- 胃肠病学 胃肠病学
- 放射学 放射学是一门学科.
- 医疗成像医学成像
背景情况:
- 使用CT肠道学测量克罗恩病狭窄的标准化方法对于临床决策和治疗试验至关重要.
- 目前的CT肠道学评估缺乏标准化指标来描述克罗恩病的狭窄性.
研究的目的:
- 评估CT肠道学特征在描述克罗恩病狭窄性的可靠性.
- 为了确定CT肠道学特征与收缩严重程度之间的相关性.
主要方法:
- 对43名成年患者进行了回顾性分析,这些患者患有有症状的乳腺缩. 克罗恩病.
- 四名放射科医生在两个会议中评估了狭窄的标准化成像特征 (连续测量和观察).
- 使用类内相关系数 (ICC) 评估了interrater可靠性;具有ICC ≥0.41的特征被认为是可靠的.
主要成果:
- 五次连续测量和六次观测显示了中等至优异的测量器间可靠性 (ICC范围,0.420.80).
- 缩长度 (ICC,0.64),最大小肠扩张 (ICC,0.80) 和最大缩壁厚度 (ICC,0.50) 独立地与缩严重程度相关 (P < .003).
- 使用这三个可靠的测量结果,我们得出了狭窄性严重性的定量模型.
结论:
- 标准化的CT肠道学测量和观察可靠地描述了终端叶克罗恩病狭窄.
- 狭窄的长度,最大相关的小肠扩张和最大的狭窄壁厚度是与克罗恩病狭窄严重程度相关的可靠指标.
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