"一个有意义的差异,但最终不是我想要的差异":一种混合方法方法来探索和比较临床上有意义的变化在失言症恢复
Sally Zingelman1,2,3, Dominique A Cadilhac3,4,5, Joosup Kim4,5
1School of Health and Rehabilitation Sciences, Queensland Aphasia Research Centre, The University of Queensland, St Lucia, Queensland, Australia.
概括
这项研究确定了中风后失语康复的最小重要变化 (MIC) 门. 患者和临床医生一致认为",略有改善"意味着中风后6个月内有意义的变化.
科学领域:
- 神经学 神经学
- 语音语言病理学 语言病理学
- 康复医学 康复医学 康复医学
背景情况:
- 在中风后失语康复中建立有意义的变化基准对于解释患者结果至关重要.
- 最小重要的变化 (MIC) 值代表患者认为重要的最小变化.
- 这项研究计划旨在定义MIC的核心结果测量仪器 (OMI) 在失言症.
研究的目的:
- 探讨有关临床上有意义的变革的失语症患者和语音病理学家的观点.
- 为了达成共识,在语障康复中MIC的门.
- 为了告知相关的OMI的发展对失言症.
主要方法:
- 一个连续的混合方法设计,涉及焦点小组和共识研讨会与调查.
- 参与者包括中风后失语症患者和语言病理学家.
- 使用反射主题分析分析了定性数据,并使用描述性统计数据报告了共识研讨会的定量数据.
主要成果:
- 关于有意义的变革,出现了四个主题:个性,持续的小改进,以目标为导向的进步和个人因素的影响.
- "略有改善"被确定为中风后6个月内MIC值 (75%-92%同意).
- 6个月后,MIC门 (达成36%-66%的协议) 趋向于"大大改善".
结论:
- 这项混合方法研究为定义MIC在失言症康复中提供了新的证据.
- 这些发现强调了患者和临床医生的观点在建立有意义的变革方面的重要性.
- 未来的研究将专注于建立在失语症中核心OMI的MIC值.
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