相关实验视频

Updated: Jun 17, 2025

Using Human Induced Pluripotent Stem Cell-derived Hepatocyte-like Cells for Drug Discovery
12:40

Using Human Induced Pluripotent Stem Cell-derived Hepatocyte-like Cells for Drug Discovery

Published on: May 19, 2018

10.2K

一个高通量查平台识别了FDA批准的抑制SREBP通路激活的药物

Chiaki T Ishida1, Casie S Kubota1, Evan Carlyle2

  • 1Department of Cell Biology, Johns Hopkins University, Baltimore, Maryland 21205 United States.

ACS chemical biology
|August 6, 2024
PubMed
概括

研究人员对FDA批准的药物进行了选,以寻找醇调控元素结合蛋白 (SREBPs) 的抑制剂,这对癌症生长至关重要. 他们确定了13种阻断SREBP通路的药物,为癌症提供了潜在的新疗法.

更多相关视频

Identification of Kinase-substrate Pairs Using High Throughput Screening11:13

Identification of Kinase-substrate Pairs Using High Throughput Screening

Published on: August 29, 2015

8.1K
A Simple Method to Identify Kinases That Regulate Embryonic Stem Cell Pluripotency by High-throughput Inhibitor Screening07:18

A Simple Method to Identify Kinases That Regulate Embryonic Stem Cell Pluripotency by High-throughput Inhibitor Screening

Published on: May 12, 2017

6.4K

相关概念视频

Drug Discovery: Overview01:26

Drug Discovery: Overview

Drug discovery is a multifaceted process involving extensive screening, testing, and optimization of lead compounds to identify potential new drugs for therapeutic use. It combines several approaches, including screening large numbers of natural products, chemical modification of known active molecules, identification of new drug targets, and rational design based on biological mechanisms and drug-receptor structure. These approaches are carried out in both academic research laboratories and...
7.7K