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三叶草 (Trifolium pratense) 作为一种新型植物性补充剂,是中的抗菌剂
Yi-Yang Lien1, Lie-Fen Shyur2, Yuan-Bin Cheng3
1Department of Veterinary Medicine, National Pingtung University of Science and Technology, Pingtung 912, Taiwan.
Poultry science
|August 6, 2024
概括
红三叶草 (Trifolium pratense) 粉末和提取物对的Eimeria寄生虫表现出强大的抗菌作用. 这种天然植物性方法有效地减少了疾病的严重程度,并改善了的健康状况,为传统药物提供了替代品.
科学领域:
- 兽医寄生虫学 兽医寄生虫学
- 禽畜科学 禽畜科学 禽畜科学
- 自然产品化学 自然产品化学
背景情况:
- 由Eimeria寄生虫引起的菌病对全球家禽产业构成重大经济威胁.
- 耐药Eimeria菌株的增加需要采用替代的控制策略.
- 植物遗传学为管理菌病和减少抗生素使用提供了一个有希望的途径.
研究的目的:
- 评估Trifolium pratense (TP) 粉末及其乙醇提取物 (TPE) 对Eimeria物种的抗菌疗效.
- 评估TP和TPE补充剂对菌感染的表现和健康的影响.
- 描述TPE的化学成分并确保其的一致性.
主要方法:
- 在体外测试中使用马丁-达比牛细胞来评估TPE对Eimeria入侵和繁殖的影响.
- 实体研究涉及感染Eimeria的,食补充了TP或TPE的饮食.
- 测量卵囊脱落,肠损伤得分,相对体重增加和代谢参数.
- 使用液体柱色谱和光谱方法对TPE进行化学指纹检测.
主要成果:
- TPE显著抑制了Eimeria maxima卵巢胞的分泌和Eimeria tenella sporozoite的入侵.
- 在受感染的中,TP和TPE补充剂显著降低了卵囊产量和肠损伤严重程度.
- 在感染了E. tenella和E. acervulina的中,TP改善了体重增加.
- 抗菌指数得分表明TP/TPE疗效优于商用菌剂安普.
- 补充TP对挑战性的初级新陈代谢产生了积极的影响.
结论:
- 三叶草 (Trifolium pratense) 对埃梅里亚 (Eimeria) 种类表现出显著的抗菌性质.
- TP和TPE作为有效的植物性补充剂,用于控制子菌病.
- 这项研究支持使用T. pratense作为传统抗菌药物的天然替代品.
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