中央睡眠呼吸暂停对阻塞性睡眠呼吸暂停儿童睡眠结构的影响
ChenXi Luo1, WenBo Chen1, Qi Li2
1Department of Otorhinolaryngology, Children's Hospital of Nanjing Medical University, Jiangsu, PR China.
International journal of pediatric otorhinolaryngology
|August 6, 2024
概括
患有阻塞性睡眠呼吸暂停 (OSA) 和中心睡眠暂停 (CSA) 的儿童表现出改变的睡眠模式. 这些包括更多的呼吸事件,较低的深度睡眠和较低的氧气和与仅患有OSA的儿童相比.
科学领域:
- 儿科睡眠医学 儿科睡眠医学
- 呼吸系统医学 呼吸系统医学
- 临床生理学 临床生理学
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 在儿童中很常见.
- 中央睡眠呼吸暂停 (CSA) 可以与OSA共存,改变呼吸和睡眠模式.
- 了解这些差异对于有效的诊断和管理至关重要.
研究的目的:
- 调查同时发生的中央睡眠呼吸暂停 (CSA) 对被诊断患有阻塞性睡眠暂停 (OSA) 的儿童睡眠模式的影响.
- 为了比较单独患有OSA的儿童和患有OSA和CSA的儿童之间的睡眠架构和临床特征.
主要方法:
- 接受多睡眠学 (PSG) 的儿童被分为两组:仅有OSA (A组) 和有CSA的OSA (B组).
- 组B满足了10-50%的CSA标准.
- 统计分析比较了两组之间的睡眠参数和临床数据.
主要成果:
- 与A组相比,B组的呼吸事件,呼吸暂停-呼吸暂停指数和氧气不和指数 (ODI) 显著高于A组.
- B组的儿童显示总睡眠时间,兴奋指数和心率增加.
- 组B显示N3睡眠阶段的时间缩短,氧化水平较低.
结论:
- 与单独患有OSA的儿童相比,患有OSA和同时患有CSA的儿童表现出不同的睡眠状况.
- 关键的差异包括N3睡眠时间的减少,唤醒指数的升高和更严重的呼吸系统障碍.
- 研究结果强调了OSA和CSA联合对儿科睡眠质量和氧化量的显著影响.
相关概念视频
Sleep Apnea
134
Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
The condition is more prevalent among...
134
Sleep-Wake Cycles
1.2K
Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
1.2K
Nightmares and Night Terrors
82
Nightmares and night terrors represent two distinct types of sleep disturbances that differ in timing, characteristics, and the sleeper's recall of the event. Nightmares are vivid, disturbing dreams that usually awaken the sleeper from REM sleep, a stage of sleep where brain activity is high, and dreams are most frequent. Upon awakening, individuals often have detailed recollections of their nightmares, which can include themes of threats to survival, security, or self-esteem.
Nightmares...
Nightmares...
82
Insufficient Sleep and Sleep Deprivation
138
Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
Sleep deprivation is a more severe form of sleep loss...
138
Cause and Effect
10.9K
While variables are sometimes correlated because one does cause the other, it could also be that some other factor, a confounding variable, is actually causing the systematic movement in our variables of interest. For instance, as sales in ice cream increase, so does the overall rate of crime. Is it possible that indulging in your favorite flavor of ice cream could send you on a crime spree? Or, after committing crime do you think you might decide to treat yourself to a cone?
10.9K
Chemical Factors Affecting Respiration Centers
1.0K
Chemical factors such as changing CO2, O2, and H+ levels in arterial blood play a critical role in influencing respiration depth and rates. These variations are detected by chemoreceptors—specialized sensors located in two primary body areas. Central chemoreceptors are found throughout the brain stem, including the ventrolateral medulla, while peripheral chemoreceptors are located in the aortic arch and carotid arteries.
CO2 has a potent influence on respiration and is strictly regulated....
CO2 has a potent influence on respiration and is strictly regulated....
1.0K


