内动脉化:内血管血栓切除术的频率,决定因素和结果的改变
Allan Q Phan1, Bryan Yoo2, David S Liebeskind3
1Department of Neurology and Comprehensive Stroke Center, UCLA, Los Angeles, CA, USA; Stanford Stroke Center, Department of Neurology and Neurological Sciences, Stanford University, Palo Alto, CA, USA.
概括
在患有大血管封闭急性缺血性中风 (LVO-AIS) 的患者中,内动脉化 (ICAC) 显示在内血管血栓切除术 (EVT) 期间具有成功反的U形链接. 广泛的ICAC可能需要更多的干预,影响结果.
科学领域:
- 神经学 神经学
- 放射学 放射学是指放射学
- 心血管科学 心血管科学
背景情况:
- 在患有大血管封闭急性缺血性中风 (LVO-AIS) 患者的CT扫描中经常观察到内动脉化 (ICAC).
- 在接受内血管血栓切除术 (EVT) 的患者中,ICAC可以作为内动脉样硬化和改变血管合规性的生物标志物.
研究的目的:
- 调查ICAC程度与接受EVT的LVO-AIS患者的结局之间的关联.
- 评估ICAC作为程序成功和临床结果的潜在预测因素.
主要方法:
- 在EVT之前接受CT头部患者的回顾性队列研究 (2016-2020).
- 通过使用一个验证的尺度来评估化厚度和周围参与度来对ICAC程度进行分级.
- 分析三种ICAC负担级别与程序,临床和安全结果之间的关系.
主要成果:
- 在包括的86名患者中,ICAC存在于72.1%的患者中.
- 在ICAC得分和成功的再输血之间发现了一个U形的关联 (p=0.008).
- 较高的ICAC分数与增加使用救援干预相关 (p=0.05),但与90天的功能独立性或症状性内出血率无关.
结论:
- 近四分之三的LVO-AIS患者在CT扫描上显示ICAC.
- ICAC的程度表明了U形关系与成功的转流,受救援干预在广泛化病例中的使用的影响.
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