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长期影响早产和妊娠年龄小的婴儿的生长:全国出生队列研究

Yi-Yu Su¹, Chi-Jen Chen², Mei-Huei Chen³

¹Institute of Environmental and Occupational Health Sciences, National Taiwan University, College of Public Health, Taipei, Taiwan; Department of Pediatrics, Taipei Medical University Hospital, Taipei, Taiwan.

Pediatrics and neonatology

|August 6, 2024

概括

过早和小于妊娠年龄 (SGA) 的婴儿通常会实现追赶增长,但过早的SGA雌性在三岁时显示肥胖风险增加. 需要进一步研究它们的长期增长轨迹.

科学领域:

儿科儿科儿科
新生儿科学新生儿科学
增长和发展增长和发展

背景情况:

过早和小于妊娠年龄 (SGA) 的婴儿面临长期的生长问题,如矮身和肥胖.
虽然追赶增长很常见,但这些婴儿仍然容易患肥胖和代谢障碍.
如果无法实现追赶增长,可能会导致病态的矮身和神经发育障碍.

研究的目的:

描述台湾早产或SGA婴儿的生长模式.
调查与早产和SGA状态相关的生长发病率.
提供台湾婴儿生长人口数据.

主要方法:

利用了台湾出生队列研究 (TBCS) 的数据,包括16,358对母婴对.
员工结构化问卷采访和三个后续调查 (6,18,36个月).
应用线性混合模型用于增长曲线分析和后勤回归用于结果建模.

主要成果:

过早生育和SGA婴儿通常表现出追赶增长,与适合妊娠年龄 (AGA) 的婴儿相比,在三岁之前没有增加身高矮或未能壮成长的风险.
在36个月的随访期间,早产SGA婴儿,特别是女性,患肥胖的几率更高.
在早产/产后SGA和早产/产后AGA婴儿之间,生长模式有所不同.

结论:

这是关于台湾SGA婴儿成长的第一个全国性,基于人口的研究.
与早产/早产AGA婴儿相比,早产/早产SGA婴儿存在不同的生长轨迹.
需要进一步研究以了解这些生长模式对健康的长期影响.

关键词:

增长的增长增长的增长国家出生队列研究.新生儿科学新生儿科学儿科儿科儿科过早生育过早生育对于妊娠年龄来说,小的

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