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准p97-Npl4相互作用抑制瘤T细胞发育,以增强瘤免疫力

Pingping Nie1,2, Zhifa Cao2, Ruixian Yu1

  • 1State Key Laboratory of Genetic Engineering, School of Life Sciences, Zhongshan Hospital, Fudan University, Shanghai, China.

Nature immunology
|August 6, 2024
PubMed
概括

酸抑制p97-Npl4复合体,对于瘤透调节T细胞至关重要. 这种药物通过影响Treg-TH17平衡来增强抗瘤免疫力,提供了一个新的免疫治疗点.

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