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Updated: Jun 17, 2025

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甲状腺激素受体ZTA-261的选择性β亚型激动剂ZTA-261的合成和临床前测试

Masakazu Nambo1,2, Taeko Nishiwaki-Ohkawa3,4, Akihiro Ito5

  • 1Institute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8601, Japan. mnambo@itbm.nagoya-u.ac.jp.

Communications medicine
|August 6, 2024
PubMed
概括

一种新的甲状腺激素类似物,ZTA-261,选择性地准THRβ以改善脂质代谢. 与现有治疗方法相比,这种类比显示毒性降低,为肥胖和失脂症药物开发提供了潜力.

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