青少年饮酒与年轻成人认知功能之间的关联:一项共同双胞胎对比研究
Megan E Cooke1, Mallory Stephenson2, Sarah J Brislin1
1Department of Psychiatry, Robert Wood Johnson Medical School, Rutgers University, Piscataway, NJ, USA.
Addiction (Abingdon, England)
|August 7, 2024
概括
青少年的酒精使用对年轻人的认知影响很小,使用量较高和词汇量较低的分数之间存在轻微的关联. 这项研究对芬兰双胞胎的遗传和环境因素进行了控制.
科学领域:
- 神经科学是一个神经科学.
- 心理学 心理学 心理学
- 遗传学 是一个遗传学.
背景情况:
- 青少年使用酒精的研究往往难以将因果关系与共同的遗传或环境因素分开.
- 尼古丁使用和其他物质并发症也会影响认知,复杂化直接的酒精认知联系.
研究的目的:
- 为了澄清青少年饮酒与年轻成年人的认知功能之间的关系.
- 区分酒精的影响与共同的病因影响,包括遗传学和同时出现的物质使用.
主要方法:
- 利用随机效应模型来控制家族结构内的测量混因素.
- 使用共同双胞胎比较,包括单胞胎 (MZ) 双胞胎对,以考虑未测量的遗传和环境因素.
- 分析了芬兰纵向FinnTwin12研究的数据,包括812个人.
主要成果:
- 青少年饮酒和中毒的频率较高与年轻成年人词汇量得分较低有关.
- 即使在对共同双胞胎分析中控制共享的遗传和环境因素之后,这些关联仍然很重要.
- 对于其他认知指标,没有发现显著的影响.
结论:
- 很少有证据表明,青少年的酒精使用在这个芬兰队列中,在年轻人成年期引起广泛的认知缺陷.
- 在青少年饮酒量较高和年轻成年人词汇减少之间存在温和的关联.
- 这些发现强调了在物质使用和认知研究中控制遗传和家族因素的重要性.
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