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通过表面微观结构提高磁螺旋式微游泳器的游泳性能

Gang Wang^1,2, Sisi Wang¹, Famin Shi¹

¹School of Physics and Electronic Science, Guizhou Normal University, Guiyang 550025, China.

Langmuir : the ACS journal of surfaces and colloids

|August 7, 2024

概括

将表面微结构引入人工细菌鞭毛 (ABF) 提高了它们的速度和效率,用于诸如药物输送等生物医学应用. 这项创新提高了微机器人的性能,以实现更快的体内和体外疗法.

科学领域:

生物医学工程生物医学工程
微流体学微流体学
机器人技术机器人技术机器人技术

背景情况:

人工细菌鞭毛 (ABF) 或磁螺旋式微游泳器,在向药物输送和微创手术方面表现有前途.
高运动效率对于ABFs的快速in vivo/in vitro治疗应用至关重要.

研究的目的:

研究表面微观结构对ABF的游泳行为和效率的影响.
探索控制微结构ABF运动的基本机制.

主要方法:

在受微生物启发的ABF中引入表面微结构.
开发和应用微结构ABF的水力动力学模型.
表面湿透性和微观结构固体分数效应的实验和分析研究.

主要成果:

微结构ABF与光滑ABF相比,具有更高的最大前进速度和退出频率.
界面滑动和流体微观结构相互作用是增强游泳表现的关键.
表面湿透性和微观结构固体分数显著影响ABF游泳动态.

结论:

表面微结构为提高ABF的速度和效率提供了有效的策略.
了解流体微结构相互作用对于设计先进的微机器人至关重要.
这项研究为生物医学应用中更快,更有效的微机器人铺平了道路.

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