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Updated: Jun 17, 2025

Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology
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Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology

Published on: March 23, 2011

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突触蛋白CSF水平与没有痴呆症的个体的记忆得分有关

Kirsten E J Wesenhagen1, Diederick M de Leeuw1, Jori Tomassen1

  • 1Alzheimer Center Amsterdam, Vrije Universiteit Amsterdam, Amsterdam UMC.

Research square
|August 7, 2024
PubMed
概括

大脑脊髓液中的突触蛋白水平与阿尔茨海默病 (AD) 早期阶段的记忆力下降相关,甚至在显著的认知障碍之前. 这些发现强调了早期的突触功能障碍作为潜在的治疗点.

关键词:
突触蛋白质是一种突触蛋白质.大脑脊髓液的蛋白质组学早期的阿尔茨海默氏症疾病.记忆表现 记忆表现 记忆表现

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