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相关概念视频

Brain Imaging01:14

Brain Imaging

219
Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
219

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Real-time fMRI Biofeedback Targeting the Orbitofrontal Cortex for Contamination Anxiety
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功能性运动障碍与异常的互感性大脑活动有关:基于任务的功能性MRI研究

Primavera A Spagnolo1,2,3, Jacob A Parker4, Mark Hallett5

  • 1Mary Horrigan Connors Center for Women's Health and Gender Biology, Brigham and Women's Hospital, Boston, MA, USA.

medRxiv : the preprint server for health sciences
|August 7, 2024
PubMed
概括

功能性运动障碍 (FMD) 与整个感知注意力期间大脑活动的改变有关,特别是在专注于与疾病相关的身体感觉时. 这表明在口炎中,身体内部状态的异常处理.

关键词:
默认模式 网络 默认模式 网络功能性运动障碍 功能性运动障碍岛屿岛屿是一个岛屿.间接接收录 (interoception) 是一种对接接收录.预测错误 预测错误 预测错误

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Functional Near Infrared Spectroscopy of the Sensory and Motor Brain Regions with Simultaneous Kinematic and EMG Monitoring During Motor Tasks
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科学领域:

  • 神经科学是一个神经科学.
  • 精神病学是一个精神病学.
  • 医疗成像医学成像

背景情况:

  • 异常整感处理是功能神经障碍 (FND) 病理生理学中提出的一种机制.
  • 之前关于FND整接收的研究结果不一致.
  • 功能性运动障碍 (FMD) 是FND的一个亚型.

研究的目的:

  • 为了研究成年人患有高动力性口病的整感觉注意力的神经相关物.
  • 为了在口病患者和健康对照者 (HCs) 之间进行整接和外接任务时比较大脑活动.
  • 检查自我报告的整体感受及其与口病中神经活动的关系.

主要方法:

  • 功能磁共振成像 (fMRI) 用于测量血液氧化水平依赖 (BOLD) 反应.
  • 在Voxelwise分析中,13名患有高动力口病的成年人与13名患有高动力口病的成年人之间的大脑活动进行了比较.
  • 参与者执行了专注于身体感觉 (心跳,胃,与疾病相关的"身体") 和外受刺激的任务.

主要成果:

  • 互感任务激活了一个网络,包括前,后 cingulate 皮质 (PCC),尾状核 (CN) 和右前半岛 (aINS).
  • 主要观察到的群体差异在于处理与疾病相关的整体感应信号,在口病中激活范围更广.
  • 与整体感应焦点 (身体与心跳/胃) 相关的大脑活动的具体差异在PCC,CN,角性,丘脑和中岛发现.

结论:

  • 这项研究提供了新的证据,将口病与异常的整体感知处理联系起来.
  • 在监测身体状态,注意力和平静推理至关重要的大脑区域中发现了异常.
  • 研究结果表明,在口病理生理学中,改变了整体感受的神经基础.