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儿童COVID-19的临床特征:伊朗的一项大型多中心研究
Azin Hajialibeig1, Mohammad Reza Navaeifar1, Amir-Hassan Bordbari2
1Pediatric Infectious Diseases Research Center, Communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran.
Frontiers in pediatrics
|August 7, 2024
概括
儿童COVID-19病例虽然往往是轻微的,但由于疫苗接种延迟而带来风险. 潜在的疾病,肥胖和胃肠道问题显著增加了儿童进入重症监护室 (ICU) 的可能性.
科学领域:
- 儿童传染病 儿童传染病
- 流行病学 流行病学
- 关键护理医学 关键护理医学
背景情况:
- 儿童COVID-19通常与成人相比呈现较轻微的症状和较低的死亡率.
- 在大流行期间推迟小儿疫苗接种增加了儿童的风险.
- 了解儿童COVID-19的疾病严重程度和风险因素对于有效管理至关重要.
研究的目的:
- 分析伊朗儿科COVID-19患者的人口特征,临床特征和疾病严重程度.
- 确定与重症监护室 (ICU) 住院和COVID-19儿童的严重结果相关的风险因素.
- 提供数据,以告知疫苗接种战略和针对弱势儿科群体的有针对性的干预措施.
主要方法:
- 一项观察性多中心研究,涉及1,031名在伊朗被诊断患有COVID-19的儿童 (0-21岁).
- 根据临床和放射性发现,患者被分为轻度,中度,严重或关键类别.
- 使用后勤回归分析来确定与ICU入院和疾病严重程度相关的因素.
主要成果:
- 发烧,咳和呼吸障碍是最常见的症状. 19.77%的住院患者需要接受ICU治疗,死亡率为0.91%.
- 患有潜在疾病,胃肠道症状和肥胖症的儿童在ICU入院的几率显著更高.
- 年龄分布在严重程度组之间有所不同,超过一半的病例发生在5岁以上的儿童中.
结论:
- 虽然儿童COVID-19死亡率较低,但某些因素,如并发病,肥胖和胃肠道症状是严重疾病和ICU入院的关键预测因素.
- 早期识别症状和危险因素对于儿童COVID-19病例的及时干预至关重要.
- 疫苗接种和有针对性的公共卫生措施对于保护儿童和减轻医疗保健系统负担至关重要.
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