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Updated: Jun 17, 2025

A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF3
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流感A病毒感染激活STAT3,以增强SREBP2表达,胆固醇生物合成和病毒复制

Jingting Zhang1, Yunhan Wu1, Yujie Wang1

  • 1College of Veterinary Medicine, Institute of Comparative Medicine, Yangzhou University, Yangzhou 225009, Jiangsu Province, China.

iScience
|August 7, 2024
PubMed
概括

甲型流感病毒感染通过激活STAT3来促进胆固醇合成,而STAT3则对SREBP2和HMGCR进行上调. 这提高了病毒的复制和细胞胆固醇水平.

关键词:
遗传学 是一个遗传学.病毒学 病毒学

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