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Updated: Jun 17, 2025

Chemical Inactivation of the E3 Ubiquitin Ligase Cereblon by Pomalidomide-based Homo-PROTACs
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由莱纳利多米德诱导的复发性Fanconi综合征:一个病例报告

Irida Sharra1, Marine Lhoir1, Jean-Marin Des Grottes2

  • 1Emergency Department, CHU Charleroi-Chimay, Charleroi, BEL.

Cureus
|August 7, 2024
PubMed
概括

芬科尼综合征 (FS) 是一种管疾病,导致尿路过度损失重要分子. 这一案例突出显示了一名因多发性骨髓瘤而接受莱纳利多米德治疗的患者的复发性FS.

关键词:
毒性毒性毒性毒性毒性毒性毒性毒性毒性毒性毒范科尼综合征是什么意思莱纳利多胺的使用方法多发性骨髓瘤是多发性骨髓瘤的一种.靠近的管 靠近的管

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Renal Failure: Dose Adjustments01:11

Renal Failure: Dose Adjustments

In patients with renal impairment, drugs undergo significant changes in their pharmacokinetics, which require dosage adjustments to ensure safe and effective therapy.
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...
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