慢性牙周炎和慢性病之间的关联的元分析
Fu Yang1, Cheng-Jun Shu1, Cai-Jun Wang1
1Department of Stomatology, Yuyao People's Hospital of Zhejiang Province, Yuyao 315400, Zhejiang Province, China.
World journal of clinical cases
|August 7, 2024
概括
慢性牙周炎 (CP) 显著增加患慢性病 (CKD) 的风险,反之亦然. 这种双向联系表明,牙周健康会随着时间的推移影响功能.
科学领域:
- 口腔卫生和脏病学
- 系统性审查和元分析
背景情况:
- 许多研究已经探索了慢性牙周炎 (CP) 和慢性病 (CKD) 之间的联系.
- 现有研究提出了相互矛盾的结论,需要进行全面的系统审查.
- 本次审查旨在澄清CP和CKD之间的关联.
研究的目的:
- 系统地调查慢性牙周炎和慢性病之间的相关性.
- 在患有慢性瘤的患者中分析牙周的参数,如临床附着水平 (CAL) 和口袋探测深度 (PPD).
主要方法:
- 在PubMed,Embase,Cochrane图书馆和Web of Science进行了系统的文献搜索,直到2024年1月.
- 提取了CP与CKD,以及CKD患者的CAL/PPD之间的关联数据.
- 使用Stata 12.0进行了统计分析,用于元分析.
主要成果:
- 对13项研究的元分析显示,CP患者的CKD概率是CP患者的1.54倍 (RR=1.54,95%CI:1.40-1.70).
- 在CKD患者中,CP发生率是CKD患者的1.98倍 (OR=1.98,95%CI:1.53-2.57).
- 与健康对照组相比,CKD患者的CAL (SMD=0.65,95%CI:0.29-1.01) 和PPD (SMD=0.33,95%CI:0.02-0.63) 显著增加.
结论:
- 慢性牙周炎和慢性病之间存在显著的双向关系.
- 患有CP的患者患有CKD的风险较高,CKD患者患有CP的发病率较高.
- 随着时间的推移,慢性病患者的牙周病进展和牙损失风险会增加.
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