在收性缺陷中视觉治疗后的神经变化:系统性审查
Laura Barberán-Bernardos1, Natalia Jiménez1, David P Piñero1,2
1Department of Optics, Pharmacology and Anatomy University of Alicante, Alicante, Spain.
Journal of ophthalmology
|August 7, 2024
概括
对收性缺陷 (CI) 的视觉治疗 (VT) 可能会导致神经变化,但目前的研究质量太低,无法证实这一点. 需要更多高质量的研究来了解VT.
科学领域:
- 神经科学是一个神经科学.
- 眼科医生 眼科 眼科
- 临床研究 临床研究
背景情况:
- 收不足 (CI) 是一种常见的双眼视力障碍.
- 视觉疗法 (VT) 是CI的主要治疗方法,但其神经支柱尚未得到充分理解.
研究的目的:
- 系统地审查有关视觉疗法 (VT) 对接近性缺陷 (CI) 患者神经影响的文献.
- 为了将观察到的神经变化与CI的VT后的临床改善相关联.
主要方法:
- 在PubMed和Scopus进行了系统的文献搜索.
- 在分析了17篇最初识别的文章后,四项研究符合纳入标准.
- 通过使用GRADE工具评估研究质量.
主要成果:
- 功能性磁共振成像 (fMRI) 研究表明,在CI的VT后,大脑区域可能发生改变,例如前部领域,眼运动虫和小脑.
- 关于功能活动变化的方向 (增加或减少) 的发现是矛盾的,可能是由于不同的fMRI协议.
- 确定了关于偏见,不一致性,间接性和不准确性风险的严重担忧,导致证据的确定性非常低.
结论:
- 目前的证据不足以证实VT在CI中的神经变化,这是由于研究质量和方法方面的担忧非常低.
- 需要进一步进行高质量的研究,以阐明VT为CI的基础的神经机制.
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