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Use of Single Chain MHC Technology to Investigate Co-agonism in Human CD8+ T Cell Activation
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在HBV小鼠模型中,TCR类双特异抗体用于消除感染肝细胞

Yang Shi1,2, Zihan Wang1,2, Jingjing Xu1,2

  • 1State Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, School of Public Health & School of Life Sciences, Xiamen University, Xiamen, People's Republic of China.

Emerging microbes & infections
|August 7, 2024
PubMed
概括

新的双特异性抗体 (BsAbs) 显示出治疗乙型肝炎病毒 (HBV) 感染的希望. 这些工程抗体将T细胞重定向以消除HBV感染的肝细胞,为完全根除提供了潜在的途径.

关键词:
抑制HBsAg的抑制作用乙型肝炎病毒的感染.类似TCR的抗体两种特定抗体的抗体.治疗性抗体治疗性抗体

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