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修改的粘膜切除术与修改的膜切除术在晚发症的原发性先天性,青少年和二次开角玻璃眼病中

Ghasem Fakhraie¹, Shabnam Ansari¹, Seyed Mehdi Tabatabaei¹

¹Glaucoma Service, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.

European journal of ophthalmology

|August 7, 2024

概括

修改后的粘膜切除术 (VCO-Tbo) 提供了改善的眼内压力 (IOP) 的控制,与标准的粘膜切除术 (Tbo) 相比,在各种类型的青光眼中. 这种增强的程序可能会导致更好的长期结果的青光眼患者.

科学领域:

眼科医生眼科眼科
玻璃眼的手术玻璃眼的手术
手术创新在外科创新.

背景情况:

青光眼的治疗通常需要进行手术以降低眼内压力 (IOP).
轨道切除术是一种通过改善水性幽默流出来治疗青光眼的手术技术.
对现有外科手术程序的修改旨在提高疗效和患者的治疗结果.

研究的目的:

为了比较修改后的粘膜切除术 (VCO-Tbo) 与标准修改后的粘膜切除术 (Tbo) 的疗效.
为了评估晚发性初级先天性,青少年开角性,类固醇诱导性和色素性玻璃眼患者的结果.

主要方法:

随机对照试验比较VCO-Tbo和Tbo组.
视内压力 (IOP) 的评估,抗白血病药物的使用,以及成功/失败率.
使用线性混合模型和卡普兰-梅尔生存分析的统计分析.

主要成果:

与Tbo组相比,VCO-Tbo组在六个月后和最终随访时显示出明显较低的IOP (分别为p=0.031和p=0.013).
这两种程序都导致药物使用量从基线显著减少,没有显著的群体间差异.
在最终随访时,VCO-Tbo的完全和合格成功率为43.9%和34.1%,而Tbo的成功率为46.8%和10.6% (p=0.040和p=0.039).

结论:

修改后的粘膜切除术和修改后的膜切除术都有效地减少了IOP和药物需求.
在修改的轨道切除术期间,将凝聚性粘弹性注射到施莱姆运河可以提高其生存时间和整体疗效.

关键词:

晚期发作的初级先天性玻璃眼.青少年开放角光眼 (juvenile open-angle glaucoma) 是一种青少年的开放角光眼.经过修改的轨道管切除术.经过修改的粘度拉皮切除术 (Viscotrabeculotomy).二次开放角视光眼的二次视光眼

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