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在桃状状细胞癌中隐藏的逆侧部转移的系统审查

Nihal Punjabi^1,2, Arjun Sharma³, Jamie Park¹

¹Department of Otolaryngology-Head and Neck Surgery, Loma Linda University Health, Loma Linda, California, U.S.A.

The Laryngoscope

|August 7, 2024

概括

在桃体状细胞癌 (TSCC) 中隐藏的逆侧结节转移发生在10%的患者中. 在晚期瘤中,患病率更高 (19%为T3/T4),这表明选择性部剖析可能对这些病例有益.

科学领域:

头部和部瘤学头部和部瘤学
手术病理学手术病理学
耳鼻喉科耳鼻喉科耳鼻喉科

背景情况:

状状细胞癌 (TSCC) 的管理包括评估结节转移.
由于手术致病率,TSCC中隐性转移的逆侧部剖析仍然存在争议.
当前的指导方针建议选择性部剖析,当隐性转移的患病率为15-20%.

研究的目的:

为了确定TSCC患者隐藏的逆侧结节转移的患病率.
根据瘤阶段和ipsilateral节点状态来评估 contralateral部剖析的诊断产量.

主要方法:

从PubMed,Embase和Web of Science数据库中对英语文章进行系统的审查.
搜索术语包括口腔大,癌瘤,淋巴结和部剖析.
两个独立的审查员对TSCC中对侧面隐藏结节转移的患病率进行了数据提取.

主要成果:

在TSCC中,隐性逆侧结节转移的总体患病率为10%.
在cT1/T2瘤中,患病率为8%,在cT3/T4瘤中为19%.
隐性转移为ipsilateral N0的1%和ipsilateral N+的12%;最常见的是部水平II (81%) 和III (19%).

结论:

在TSCC中选择性逆侧部剖析可以在19%的T3/T4瘤中确定隐性阳性.
对T1/T2 (8%) 或N0 (1%) 瘤的诊断产量较低.
在咨询后,可以考虑对患者进行逆侧节点采样;需要对节点特征进行进一步的研究.

关键词:

的反担保.这是一个元分析.隐秘的奥秘是什么?状细胞癌 (SCLC) 是一种状细胞癌.桃体癌:桃体癌是一种癌症.

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