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Updated: Jun 17, 2025

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对CB1大麻素受体信号的负度调节降低了静脉注射吗啡自我给药和小鼠的复发

Idaira Oliva1, Fezaan Kazi1, Lucas N Cantwell2

  • 1Department of Psychological and Brain Sciences, Indiana University Bloomington, Bloomington, Indiana, USA.

Addiction biology
|August 7, 2024
PubMed
概括

用GAT358对CB1大麻素受体 (CB1R) 的负性全调节减少了小鼠的吗啡摄入量和复发行为. 这表明CB1R NAM为阿片类药物滥用提供了一种安全的治疗策略.

关键词:
大麻素受体 1 1 大麻素受体这是吗啡吗啡.动机 激励 动机负基调节器是负基调节器在阿片类药物阿片类药物.增强的强化 加强的加强自主管理的自治.

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