单边乳腺炎是系统性红斑狼的第一个症状
Heejin Yoon1,2, Junghyo Ahn1,2
1Department of Ophthalmology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Korea.
The Journal of craniofacial surgery
|August 7, 2024
概括
系统性红斑狼 (SLE) 最初可以表现为乳腺腺炎,眼腺炎. 早期诊断和免疫抑制疗法对于管理复发病例和预防进一步的并发症至关重要.
科学领域:
- 眼科医生 眼科 眼科
- 类风湿病学 类风湿病学
- 免疫学 免疫学 免疫学
背景情况:
- 乳腺腺炎,眼腺炎,可以呈现与周围轨道胀和疼痛.
- 系统性红斑狼 (SLE) 是一种慢性自身免疫性疾病,具有多样化的临床表现.
- 结核病的初始表现可以变化,有时模仿局部炎症状况.
研究的目的:
- 报告一个乳腺炎病例作为系统性红斑狼最初出现的症状.
- 强调在复发性乳腺炎的情况下考虑全身性自身免疫性疾病的重要性.
- 在这样的演讲中讨论诊断和治疗方面的挑战.
主要方法:
- 一份病例报告详细介绍了一名42岁的女性,患有复发性左腺炎.
- 临床检查,计算机断层扫描 (CT) 扫描与对比度用于轨道成像.
- 针对自身免疫标志物的实验室调查和SLE的诊断.
- 用皮质类固醇治疗,其次是免疫抑制疗法 (氧化和阿扎西奥普林).
主要成果:
- 患者呈现出周围轨道胀和疼痛,诊断为乳腺炎.
- 最初用高剂量的皮质类固醇治疗导致了暂时的改善,但发生了反复发作.
- 随后的实验室测试证实了全身性红斑狼 (SLE).
- 用氧化和阿扎西奥普林治疗导致在6个月的随访期间没有复发.
结论:
- 乳腺炎可能是系统性红斑狼的不寻常但显著的初始表现.
- 对于患有复发性乳腺炎的患者来说,迅速和彻底的调查是必不可少的.
- 组合免疫抑制疗法在治疗乳腺炎的SLE治疗中是有效的,导致持续缓解.
相关概念视频
Drug Toxicity: Allergic Reactions
209
Drug-related allergies are immune-mediated responses triggered by the administration of pharmacological agents. These hypersensitivity reactions are classified based on the immune mechanisms involved. The four primary types—Type I, II, III, and IV—are mediated by different immunological pathways and exhibit distinct clinical manifestations.Type I Hypersensitivity/ IgE-Mediated Reactions: Immunoglobulin E (IgE) immediately mediates Type I hypersensitivity reactions. Upon initial...
209
Endocarditis II: Clinical Features of Infective Endocarditis
929
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
929
Rheumatic Heart Disease I: Introduction
1.0K
Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
1.0K
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
1.3K
The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
1.3K
Nephrotic Syndrome I : Introduction
1.2K
Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of...
1.2K
Multiple Sclerosis l: Introduction
20
Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...
20


