克里普托斯波里迪亚 spp. 在中国26个省份的捕获蛇中:流行率,分子特征和症状
Yilei Zhang1, Zhenxiao Lu1, Lingru He1
1College of Animal Science and Technology, Anhui Agricultural University, Hefei, Anhui Province 230036, PR China.
Parasite (Paris, France)
|August 7, 2024
概括
克里普托斯波里迪亚 spp. 感染在蛇中很常见,在有症状的个体中流行率更高. 这项研究确定了特定物种,并将它们与中国蛇的临床症状联系起来.
科学领域:
- 兽医寄生虫学 兽医寄生虫学
- 类学 类学 类学 类学
- 分子诊断学 分子诊断
背景情况:
- 蛇被认为是物,并在中国传统医学中被使用.
- 克里普托斯波里迪亚 spp. 是重要的蛇病原体,引起胃肠道疾病.
- 感染风险因素和临床症状在Cryptosporidium物种之间可能有所不同.
研究的目的:
- 调查Cryptosporidium spp.的流行率和遗传多样性. 在中国各地的蛇中.
- 为了确定与蛇中Cryptosporidium感染相关的危险因素.
- 为了将特定的Cryptosporidium物种与症状蛇的临床表现相关联.
主要方法:
- 从中国26个省份的603只无症状蛇和147只有症状蛇收集了便样本.
- 嵌套聚合酶连锁反应 (PCR) 放大了部分小子单元 (SSU) rRNA基因用于Cryptosporidium检测.
- 鉴定的Cryptosporidium spp. 的遗传特征和进化关系. 进行了评估.
主要成果:
- 总体而言,无症状蛇的Cryptosporidium患病率为20%,症状蛇的患病率为70%.
- 年龄是无症状蛇感染的重要危险因素.
- 在有症状的蛇中发现了Cryptosporidium serpentis和Cryptosporidium varanii,其中C. serpentis与反有关,而C. varanii与腹有关.
结论:
- 这项研究提供了第一个关于Cryptosporidium spp.的报告. 和相关的临床迹象在中国的症状蛇.
- 了解Cryptosporidium感染动态和临床症状对于控制蛇的疾病至关重要.
- 这些发现有助于管理物和药用蛇的密码菌病.
相关概念视频
01:05Single Nucleotide Polymorphisms-SNPs
15.1K
A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
15.1K
01:28Fungal Phylum Microsporidia
787
Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
787