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Updated: May 6, 2026

Yeast As a Chassis for Developing Functional Assays to Study Human P53
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Yeast As a Chassis for Developing Functional Assays to Study Human P53

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通过固态NMR光谱和分子动力学模拟的脂质膜透P53的分子机制

Mingyue Li1, Jianguo Li2,3, Xingyu Lu1,4

  • 1Pharmaceutical Sciences and Clinical Supply, Merck & Co., Inc., Rahway, New Jersey 07065, United States.

Journal of the American Chemical Society
|August 7, 2024
PubMed
概括

这是一种宏环,可以穿过细胞膜. -π相互作用和动态脂质相互作用促进它们的转移,克服了细胞内药物输送的关键障碍.

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Abnormal Proliferation

Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the...
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