结性脊柱炎和脑血管疾病之间的关系:一个系统性审查
Mohammad Mahdi Heidari1, Azad Khaledi2,3, Amir Mohammad Taravati4
1Department of Pediatrics, Kashan University of Medical Sciences Faculty of Medicine, Kashan, Iran.
The Eurasian journal of medicine
|August 7, 2024
概括
结性脊柱炎患者面临更高的脑血管事件的风险,如中风. 这种与炎症和动脉样硬化相关的风险增加需要进一步调查导致因素.
科学领域:
- 类风湿病学 类风湿病学
- 神经学 神经学
- 心脏病学 心脏病学
背景情况:
- 结性脊柱炎 (AS) 与大脑血管事件的增加有关.
- 炎症,加速动脉样硬化和内皮功能障碍与AS相关的脑血管风险有关.
- 对这种联系缺乏全面的审查.
研究的目的:
- 系统地审查和综合有关结性脊柱炎和脑血管疾病之间的联系的证据.
- 与普通人群相比,评估AS患者的脑血管风险.
主要方法:
- 在Web of Science,PubMed,Medline,Scopus和EMBASE进行了系统的文献搜索.
- 包括2000年至2023年6月发表的研究.
- 分析了观察和队列研究,比较AS患者与对照者的脑血管风险 (中风,心肌梗塞).
主要成果:
- 大多数研究表明,与普通人群相比,AS患者的脑血管疾病风险更高.
- 心血管疾病的患病率随着年龄的增长而增加,在AS队伍中的两性都会增加.
- 脑血管事故的发生率在AS患者中高于对照组,尽管AS年轻患者中风风险显示出混合的发现.
结论:
- 结性脊柱炎患者通常表现出脑血管疾病的风险较高.
- 这种增加的风险受到多种因素的影响,需要进一步深入研究.
- 了解这些因素对于AS的有针对性的预防和管理策略至关重要.
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