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尼莫样酶通过准AML中的瘤抑制剂C/EBPα来阻断髓状细胞分化

Anil Kumar Singh1,2, Gatha Thacker1, Vishal Upadhyay1,2

  • 1Division of Cancer Biology, CSIR-Central Drug Research Institute, Lucknow, India.

The FEBS journal
|August 7, 2024
PubMed
概括

尼莫样类激酶 (NLK) 酸化CCAAT/增强剂结合蛋白α (C/EBPα),导致其降解并抑制髓质分化. 向NLK恢复了C/EBPα水平,并促进了急性髓性白血病的分化.

关键词:
在C/EBPα中.在NLK中,NLK是NLK.急性骨髓性白血病 (AML) 是一种急性骨髓性白血病.酸化的方法是:光化.无处不在的化

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