[使用前列腺癌抗雄激素疗法为例的老年人思维]
A Wiedemann1, A Manseck2, J Stein3
1Evangelisches Krankenhaus Witten gGmbH, Urologische Klinik, Lehrstuhl für Geriatrie, Universität Witten/Herdecke, Pferdebachstr. 27, 58455, Witten, Deutschland. awiedemann@evk-witten.de.
Urologie (Heidelberg, Germany)
|August 7, 2024
概括
由于老年患者的脆弱性,因此需要仔细规划治疗. 综合老年医学评估对于识别缺陷和管理治疗风险至关重要,以保持自主性和生活质量.
科学领域:
- 老年瘤学 老年瘤学
- 临床老年病学 临床老年病学
- 基于证据的医学基于证据的医学.
背景情况:
- 老年患者 (75岁以上的多病症患者或80岁以上的老年患者) 特别容易受到治疗副作用的影响,可能导致失去自主权.
- 在老年人中,未经管理的治疗并发症可能导致不可逆转的功能衰退.
- 标准的瘤治疗可能无法充分考虑老年人的特定需求和风险.
研究的目的:
- 强调为老年癌症患者量身定制治疗策略的必要性.
- 强调在开始治疗之前识别和解决功能缺陷的重要性.
- 倡导进行彻底的风险效益分析,考虑对日常生活和自主性的影响.
主要方法:
- 使用查工具,如风险老年人识别 (ISAR) 和老年8 (G8) 评分.
- 进行详细的老年病评估,包括病史和专业评估,以确定功能缺陷.
- 系统地记录治疗要求和对患者自主性和日常生活的潜在影响.
主要成果:
- 查工具可以有效地识别需要专门评估的老年患者.
- 功能缺陷的结构化识别允许个性化治疗规划.
- 对于老年患者来说,考虑治疗副作用对日常生活的影响至关重要.
结论:
- 老年患者的瘤治疗不应该在没有全面的老年评估之前开始.
- 功能缺陷和潜在副作用的积极管理对于保持自主性和生活质量至关重要.
- 仔细的风险效益分析,特别是对于诸如前列腺癌中雄激素剥夺疗法之类的治疗,至关重要.
相关概念视频
Menopause
146
Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...
146
Disorders of the Male Reproductive System
370
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
370
Aging
40
Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
40
Parkinson's Disease: Treatment
241
Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
241
Bone Disorders
3.5K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
3.5K
Cancer Therapies
7.6K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
7.6K


