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Updated: Jun 17, 2025

Embryo Microinjection and Electroporation in the Chordate Ciona intestinalis
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ZFP36L1和ZFP36L2通过减少E2F1的表达和CCND1转录的长3'UTR异形的表达来降低环林D1的表达

Tze-Sian Chan1,2, Kun-Lin Lee3, Ching-Sheng Hung4,5

  • 1Division of Gastroenterology, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.

Molecular and cellular biochemistry
|August 7, 2024
PubMed
概括

在结直肠癌细胞中,ZFP36L1和ZFP36L2蛋白降低林D1 (CCND1) mRNA的下调,特别是长异型. 这种调节涉及减少E2F1转录,并通过AU丰富元素 (ARE) 促进CCND1mRNA衰变.

关键词:
3 UTR 其他CCND1 一个人的生活结肠直肠癌是一种癌症.在 ZFP36L1 中.在 ZFP36L2 中.

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