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使用3D打印进行大动脉动脉瘤模拟的元材料设计.

Arthur K F Sakai1, Ismar N Cestari2, Eraldo de Sales2

  • 1Electrical Engineering Graduate Program, Telecommunications and Control Engineering Department, Polytechnic School, University of São Paulo, São Paulo, Brazil.

3D printing in medicine
|August 7, 2024
PubMed
概括

使用聚合物和元材料的三维 (3D) 打印模型显示出类似于大动脉组织的机械性能. 3D打印材料中的格子增强可以调整生物力学反应,用于模拟大动脉状况.

关键词:
通过3D打印打印3D打印.大动脉动脉瘤是一个大动脉动脉瘤.生物力学 生物力学超材料是什么?超材料是什么?

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科学领域:

  • 生物医学工程 生物医学工程
  • 材料科学 材料科学 材料科学

背景情况:

  • 三维 (3D) 打印越来越多地用于研究和临床决策中的解剖模型.
  • 研究聚合物和元材料来模仿大动脉血管壁的生物力学对于先进的医学建模至关重要.

研究的目的:

  • 评估3D打印聚合物和元材料的机械性能,以模仿大动脉生物力学.
  • 将这些印刷材料的机械特性与健康的动脉动脉和动脉瘤动脉相比较.

主要方法:

  • 在使用刚性 (VeroTM) 和柔性 (Agilus30TM) 聚合物的3D打印样本上进行了单轴拉伸测试.
  • 超材料是用格子增强器 (链条,针织,原木,钻石晶体图案) 设计的,以调整机械性能.
  • 机械性能与大动脉组织的已发表数据进行了比较.

主要成果:

  • 格子增强增加了材料刚性和3D打印样本的最大应力产生.
  • 在最大应力时的应变受到格子图案,材料类型和基材的影响.
  • 打印样本表现出最大应力从0.39 ± 0.01 MPa到0.88 ± 0.02 MPa,最大应力时的应力从70.44 ± 0.86%到158.21 ± 8.99%.

结论:

  • 3D打印模型的最大应力与大动脉组织的报告值非常接近.
  • 虽然不能完美复制生物组织,但这些模型显示出模拟大动脉生物力学的潜力,包括腹部大动脉动脉瘤.