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在接受桃体切除术的PFAPA患者中,出现立即术后发烧的风险
Ory Madgar1, Amber D Shaffer2, David H Chi2
1Division of Pediatric Otolaryngology, Children's Hospital of Pittsburgh UPMC, Pittsburgh, PA, USA; Department of Otolaryngology, Head and Neck Surgery, Sheba Medical Center, Tel-Hashomer, Israel; Faculty of Medicine, Tel-Aviv University, Israel.
American journal of otolaryngology
|August 7, 2024
概括
患有周期性发烧,口腔口炎,耳炎和宫腺炎 (PFAPA) 综合征的患者在桃体切除术后不会面临立即术后发烧的风险增加. 这项研究发现发烧的发病率很低,这表明目前的管理方案可能过于谨慎.
科学领域:
- 儿科耳鼻喉科 儿科耳鼻喉科
- 儿科风湿病学 儿科风湿病学
- 传染性疾病 传染性疾病
背景情况:
- 周期性发烧,口腔口炎,耳炎和宫腺炎 (PFAPA) 综合征是儿童最常见的周期性发烧综合征.
- 桃体切除术是PFAPA综合征的潜在治疗方法.
- 一个常见的临床担忧是PFAPA患者的术后发烧增加的可能性,这会使诊断和管理复杂化.
研究的目的:
- 为了评估患有PFAPA综合征的儿童接受桃体切除手术后立即出现手术后发烧的发生率.
- 为了确定PFAPA患者与接受桃体切除术的一般儿科患者相比,患上术后发烧的风险更高.
主要方法:
- 在高等儿童医院接受了桃体切除术的PFAPA患者 (2013-2022) 的回顾性图表审查.
- 在同一时期查询儿科健康信息系统 (PHIS) 数据库的儿科桃体切除术和PFAPA诊断.
- 对PFAPA患者手术后立即发烧率的分析.
主要成果:
- 只有1.6%的PFAPA患者 (61人中有1人) 经历了手术后立即发烧.
- 在PFAPA患者中,发烧发作的发病率在桃体切除术后显著下降 (100%手术前与9.75%手术后).
- 对大型国家数据库 (PHIS) 的分析显示,0.25%的儿科桃体切除术与PFAPA有关,在这个小组中没有报告立即术后发烧.
结论:
- 该研究表明,PFAPA综合征与桃体切除术后立即术后发烧的风险增加无关.
- 这些发现挑战了这样一个观点,即PFAPA患者仅仅因为桃体切除术后发烧风险而需要主要中心的专业护理.
- 根据这些结果,关于接受桃体切除术的PFAPA患者管理的当前机构实践可能需要重新评估.
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