温度和姿势对区域血流和血液动力学的综合影响
Jason T Fisher1, Urša Ciuha2, Igor B Mekjavić2
1Department of Automatics, Biocybernetics, and Robotics, Jozef Stefan Institute, Ljubljana, Slovenia; International Postgraduate School Jozef Stefan, Jamova 39, SI-1000, Ljubljana, Slovenia.
Journal of thermal biology
|August 7, 2024
概括
研究热量和姿势如何影响血液流动,这项研究发现,随着热量增加,手臂的血液流动增加,而站立时腿部的血液流动减少. 这两个因素都会影响心率和血压.
科学领域:
- 人体生理学 人体生理学
- 热调节 热调节 热调节
- 心血管监管 监管心血管系统
背景情况:
- 维持血压和温度调节需要在热量和姿势压力相结合的过程中整合区域血流反应.
- 在这些条件下,了解不同身体区域的微血管血流是如何调节的,对于生理适应至关重要.
研究的目的:
- 评估环境温度和身体姿势对手臂和腿部微血管血流的区域调节的影响.
- 研究温度调节和巴罗受体机制之间的相互作用,以控制区域血流.
主要方法:
- 11名参与者在气候室中进行了两次会议,湿度控制.
- 环境温度暂时升高,然后降低,而参与者要么站立,要么躺卧.
- 连续测量包括前臂和小腿皮肤血流 (SkBF),心率 (HR),中风体积 (SV),心率 (CO) 和血压 (BP);心率变化和波形变换分析也进行了.
主要成果:
- 在更高的环境温度下,前臂皮肤血流 (SkBFarm) 显著增加,而小牛皮肤血流 (SkBFcalf) 则没有.
- 无论温度如何,站立姿势始终降低了双臂和双腿的整体SkBF.
- 由于热和站立,观察到升高的HR和BP,以及降低的SV,而CO保持不变. 在峰值温度下,站立放大了交感和小牛肌原激活.
结论:
- 手臂血管通过温度调节和巴罗受体活动进行调节.
- 腿部血管表现出对巴罗反射调节机制更大的敏感性.
- 热量和姿势压力的结合显著影响区域微血管血流和心血管反应.
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