营养不良和老年患者的死亡率之间的相关性90岁以上的老年患者具有多重疾病
Yangxi Chen1, Lika Liu1, Xiang Yang2
1Department of Geriatrics, Affiliated Jinling Hospital, Southern Medical University, Nanjing 210002, Jiangsu, PR China; Department of Geriatrics, Jinling Hospital, Affiliated Hospital of Medical School, Nan jing University, Nanjing 210002, Jiangsu, PR China.
概括
患有多种疾病的老年患者 (≥90岁) 的营养不良是死亡的重要预测因素. 营养评估如MNA,GNRI和PNI有效地识别风险人群并改善死亡率预测.
科学领域:
- 老年医学 老年医学
- 营养科学 营养科学
- 流行病学 流行病学
背景情况:
- 营养不良在老年人中很常见,并与不良健康结果有关.
- 90岁及以上的老年患者具有多种疾病,是脆弱群体.
- 有效的营养评估对于预测这个群体的预后至关重要.
研究的目的:
- 评估三个营养工具的预后价值:迷你营养评估 (MNA),老年营养风险指数 (GNRI) 和预后营养指数 (PNI).
- 确定这些营养指标对中国非常老年多病症患者全因死亡率的增量预测能力.
主要方法:
- 分析了160名年龄≥90岁,多病症患者的队列.
- 用MNA,GNRI和PNI评估营养状况.
- 包括卡普兰-梅尔曲线和考克斯回归在内的生存分析被用来评估死亡风险.
主要成果:
- 很大一部分参与者 (58.1%由MNA,45.0%由GNRI,25.6%由PNI) 被认定为营养不良.
- 与幸存者相比,已故患者的MNA,GNRI和PNI得分较低.
- 由MNA,GNRI和PNI评估的营养不良是死亡率的独立预测因素 (调整后的HR从1.650到2.894不等).
结论:
- 通过MNA,GNRI和PNI评估的营养状况是长寿多病症患者死亡率的关键独立预测指标.
- 将这些营养评估工具纳入生存模型可以显著提高它们对死亡率的预测准确性.
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