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组织特异性激活胰岛素信号作为肥胖相关代谢障碍的潜在目标

Hideyuki Okuma1, Kyoichiro Tsuchiya1

  • 1Department of Diabetes and Endocrinology, Graduate School of Interdisciplinary Research, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi 4093898, Japan.

Pharmacology & therapeutics
|August 7, 2024
PubMed
概括

增强脂肪组织中的胰岛素信号传递,而不是肝脏,通过促进健康脂肪扩张和防止子宫外脂肪积累,为与肥胖有关的疾病提供了治疗策略. 了解组织特异性胰岛素抵抗是开发有效治疗的关键.

关键词:
糖尿病 糖尿病 糖尿病健康的脂肪扩张健康的脂肪扩张肝脏肥胖症 肝脏肥胖症胰岛素的信号传递.

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