相关实验视频

Updated: Jun 17, 2025

Visualizing Field Data Collection Procedures of Exposure and Biomarker Assessments for the Household Air Pollution Intervention Network Trial in India

Visualizing Field Data Collection Procedures of Exposure and Biomarker Assessments for the Household Air Pollution Intervention Network Trial in India

Published on: December 23, 2022

日本的[a]pyrene的长期空间时间变化:环境度,人类暴露和健康风险的显著下降

Shin Araki¹, Hikari Shimadera¹, Satoru Chatani²

¹Graduate School of Engineering, Osaka University, Suita, 565-0871, Japan.

Environmental pollution (Barking, Essex : 1987)

|August 7, 2024

概括

2000年至2018年,日本的[a]烯 (BaP) 含量显著下降了70%,从2000年到2018年,日本的[a]烯含量显著下降了70%. 这种减少致癌性空气污染物暴露与潜在的肺癌病例减少有关,有助于健康研究.

科学领域:

环境科学环境科学
公共卫生公共卫生
毒理学毒理学毒理学

背景情况:

甲 (BaP) 是已知的人类致癌物,但其在环境暴露水平上的健康影响需要进一步调查.
了解BaP的时空分布对于评估公共卫生风险至关重要.

研究的目的:

在1公里分辨率下估计日本本佐[a]烯 (BaP) 的长期时空变化.
为环境暴露对健康影响的流行病学研究提供准确的BaP分布数据.

主要方法:

采用整体机器学习方法来估计年度BaP度.
使用的预测因素包括标准空气污染物,排放,气象数据,土地使用和交通变量.
使用基于位置的交叉验证验证验证模型性能,实现R2为0.693.

主要成果:

人口密集的地区呈现出更高的BaP水平和更大的时间减少.
工业区持续显示出更高的BaP度.
人口加权的BaP下降了约70%,从2000年的0.44 ng m−3降至2018年的0.12 ng m−3.
暴露在10−5以上的癌症风险水平 (0.12 ng m−3) 以下的比例在2018年达到67%.

结论:

这项研究成功地绘制了日本在20多年中精细分辨率的时空BaP变化.
估计BaP暴露的减少与肺癌发病率降低的风险相关.
产生的数据对未来关于环境BaP对健康影响的流行病学研究有价值.

关键词:

空气污染大气污染组合模型模型组合模型肺癌是一种肺癌.机器学习机器学习多环芳香碳化合物多环芳香碳化合物

更多相关视频

Quantification of three DNA Lesions by Mass Spectrometry and Assessment of Their Levels in Tissues of Mice Exposed to Ambient Fine Particulate Matter

Quantification of three DNA Lesions by Mass Spectrometry and Assessment of Their Levels in Tissues of Mice Exposed to Ambient Fine Particulate Matter

Published on: May 29, 2019

Analysis of the Ambient Particulate Matter-induced Chromosomal Aberrations Using an In Vitro System

Analysis of the Ambient Particulate Matter-induced Chromosomal Aberrations Using an In Vitro System

Published on: December 21, 2016

相关概念视频

Types of Toxins

Types of Toxins

Humans continually engage with an environment rich in potentially harmful chemicals. These are introduced to our bodies through inhalation, ingestion, or skin contact. These chemicals exist in various forms, such as air and environmental pollutants, agricultural chemicals, organic solvents, and heavy metals.
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...

Biological Effects of Radiation

Biological Effects of Radiation

All radioactive nuclides emit high-energy particles or electromagnetic waves. When this radiation encounters living cells, it can cause heating, break chemical bonds, or ionize molecules. The most serious biological damage results when these radioactive emissions fragment or ionize molecules. For example, α and β particles emitted from nuclear decay reactions possess much higher energies than ordinary chemical bond energies. When these particles strike and penetrate matter, they...